Drug interactions
Insulin degludec-insulin aspart + Nebivolol
Severity: Minor
Insulin degludec-insulin aspart and Nebivolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Nebivolol may blunt tachycardia and tremor from hypoglycemia in insulin-treated patients. Its beta-1 selectivity makes the effect on glucose recovery smaller, but awareness of low glucose can still be reduced.
What this interaction means in plain words
Insulin degludec-insulin aspart and Nebivolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Insulin degludec-insulin aspart belongs to Endocrine; Nebivolol belongs to Cardiovascular.
Why it happens
Beta-1 selective blockade masks some adrenergic hypoglycemia symptoms.
What to do
Continue routine glucose monitoring and tell the patient that sweating may be the main warning sign. Adjust insulin if glycemic control changes.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Insulin degludec-insulin aspart
- Chlorpropamide + Insulin degludec-insulin aspart Major
- Clozapine + Insulin degludec-insulin aspart Major
- Diazoxide + Insulin degludec-insulin aspart Major
- Ethanol + Insulin degludec-insulin aspart Major
- Insulin degludec-insulin aspart + Mecasermin Major
- Insulin degludec-insulin aspart + Pioglitazone Major
Other interactions of Nebivolol
- Acebutolol + Nebivolol Major
- Aldesleukin + Nebivolol Major
- Amiodarone + Nebivolol Major
- Atenolol-chlorthalidone + Nebivolol Major
- Atenolol + Nebivolol Major
- Betaxolol + Nebivolol Major
Frequently asked questions
Can I take Insulin degludec-insulin aspart with Nebivolol?
MediHelp rates the interaction as minor. Insulin degludec-insulin aspart and Nebivolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Nebivolol may blunt tachycardia and tremor from hypoglycemia in insulin-treated patients. Its beta-1 selectivity makes the effect on glucose recovery smaller, but awareness of low glucose can still be reduced.
How serious is the interaction between Insulin degludec-insulin aspart and Nebivolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Continue routine glucose monitoring and tell the patient that sweating may be the main warning sign. Adjust insulin if glycemic control changes.
What other medicines interact with Insulin degludec-insulin aspart?
MediHelp also lists interactions of Insulin degludec-insulin aspart with, for example, Chlorpropamide, Clozapine, Diazoxide. The full list is on the Insulin degludec-insulin aspart page.
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