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Drug interactions

Insulin degludec-liraglutide + Lanreotide

Severity: Moderate

Insulin degludec-liraglutide and Lanreotide: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Somatostatin analogs such as lanreotide suppress insulin, glucagon and growth hormone, so glucose may fall or rise unpredictably. Insulin and liraglutide requirements may change.

What this interaction means in plain words

Insulin degludec-liraglutide and Lanreotide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Insulin degludec-liraglutide belongs to Endocrine; Lanreotide belongs to Endocrine.

Evidence level: Moderate

Why it happens

Lanreotide inhibits secretion of insulin, glucagon and counterregulatory hormones, altering glucose control.

What to do

Monitor glucose more often when starting, stopping or changing lanreotide dose. Adjust insulin dose accordingly.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Insulin degludec-liraglutide with Lanreotide?

MediHelp rates the interaction as moderate. Insulin degludec-liraglutide and Lanreotide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Somatostatin analogs such as lanreotide suppress insulin, glucagon and growth hormone, so glucose may fall or rise unpredictably. Insulin and liraglutide requirements may change.

How serious is the interaction between Insulin degludec-liraglutide and Lanreotide?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor glucose more often when starting, stopping or changing lanreotide dose. Adjust insulin dose accordingly.

What other medicines interact with Insulin degludec-liraglutide?

MediHelp also lists interactions of Insulin degludec-liraglutide with, for example, Albiglutide, Chlorpropamide, Clozapine. The full list is on the Insulin degludec-liraglutide page.

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