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Drug interactions

Insulin icodec + Lanreotide

Severity: Moderate

Insulin icodec and Lanreotide: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Lanreotide, like other somatostatin analogues, can alter insulin and glucagon secretion, causing either hypoglycemia or hyperglycemia. This may change insulin requirements, and the long action of icodec makes corrections slow.

What this interaction means in plain words

Insulin icodec and Lanreotide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Insulin icodec belongs to Endocrine; Lanreotide belongs to Endocrine.

Evidence level: Moderate

Why it happens

Somatostatin analogue inhibition of insulin, glucagon and growth hormone secretion.

What to do

Increase glucose monitoring around initiation or dose changes of lanreotide and adjust the icodec dose based on readings.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Insulin icodec with Lanreotide?

MediHelp rates the interaction as moderate. Insulin icodec and Lanreotide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lanreotide, like other somatostatin analogues, can alter insulin and glucagon secretion, causing either hypoglycemia or hyperglycemia. This may change insulin requirements, and the long action of icodec makes corrections slow.

How serious is the interaction between Insulin icodec and Lanreotide?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Increase glucose monitoring around initiation or dose changes of lanreotide and adjust the icodec dose based on readings.

What other medicines interact with Insulin icodec?

MediHelp also lists interactions of Insulin icodec with, for example, Hydroxychloroquine, Octreotide. The full list is on the Insulin icodec page.

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