Drug interactions
Ipratropium-salbutamol + Lenvatinib
Severity: Moderate
Ipratropium-salbutamol and Lenvatinib: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lenvatinib can prolong the QT interval and cause electrolyte disturbances, and salbutamol may add to this risk through hypokalemia and cardiac stimulation. The combination may increase arrhythmia risk in vulnerable patients.
What this interaction means in plain words
Ipratropium-salbutamol and Lenvatinib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ipratropium-salbutamol belongs to Respiratory; Lenvatinib belongs to Oncology.
Why it happens
Additive QT prolongation, with beta-agonist-induced hypokalemia.
What to do
Monitor ECG and correct potassium, magnesium and calcium abnormalities during lenvatinib therapy. Limit salbutamol to what is clinically needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ipratropium-salbutamol
Other interactions of Lenvatinib
- Amiodarone + Lenvatinib Major
- Amisulpride + Lenvatinib Major
- Asenapine + Lenvatinib Major
- Chlorpromazine + Lenvatinib Major
- Donepezil + Lenvatinib Major
- Haloperidol + Lenvatinib Major
Frequently asked questions
Can I take Ipratropium-salbutamol with Lenvatinib?
MediHelp rates the interaction as moderate. Ipratropium-salbutamol and Lenvatinib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lenvatinib can prolong the QT interval and cause electrolyte disturbances, and salbutamol may add to this risk through hypokalemia and cardiac stimulation. The combination may increase arrhythmia risk in vulnerable patients.
How serious is the interaction between Ipratropium-salbutamol and Lenvatinib?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and correct potassium, magnesium and calcium abnormalities during lenvatinib therapy. Limit salbutamol to what is clinically needed.
What other medicines interact with Ipratropium-salbutamol?
MediHelp also lists interactions of Ipratropium-salbutamol with, for example, Amisulpride, Arsenic trioxide, Carvedilol. The full list is on the Ipratropium-salbutamol page.
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