Drug interactions
Isocarboxazid + Maraviroc
Severity: Moderate
Isocarboxazid and Maraviroc: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs can cause postural hypotension, so combined use may increase the risk of dizziness, falls and syncope. The effect is most relevant at initiation and with dose increases.
What this interaction means in plain words
Isocarboxazid and Maraviroc can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Isocarboxazid belongs to Central Nervous System; Maraviroc belongs to Anti Virals.
Why it happens
Additive pharmacodynamic hypotensive effects; maraviroc is not known to alter MAO activity.
What to do
Monitor blood pressure, including orthostatic readings, when starting or adjusting either drug. Advise patients to rise slowly.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Isocarboxazid
- 5-HTP + Isocarboxazid Contraindicated
- Amitriptyline + Isocarboxazid Contraindicated
- Amobarbital + Isocarboxazid Contraindicated
- Amoxapine + Isocarboxazid Contraindicated
- Apraclonidine + Isocarboxazid Contraindicated
- Atomoxetine + Isocarboxazid Contraindicated
Other interactions of Maraviroc
- Amobarbital + Maraviroc Major
- Apalutamide + Maraviroc Major
- Carbamazepine + Maraviroc Major
- Clarithromycin + Maraviroc Major
- Efavirenz + Maraviroc Major
- Enzalutamide + Maraviroc Major
Frequently asked questions
Can I take Isocarboxazid with Maraviroc?
MediHelp rates the interaction as moderate. Isocarboxazid and Maraviroc can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs can cause postural hypotension, so combined use may increase the risk of dizziness, falls and syncope. The effect is most relevant at initiation and with dose increases.
How serious is the interaction between Isocarboxazid and Maraviroc?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, including orthostatic readings, when starting or adjusting either drug. Advise patients to rise slowly.
What other medicines interact with Isocarboxazid?
MediHelp also lists interactions of Isocarboxazid with, for example, 5-HTP, Amitriptyline, Amobarbital. The full list is on the Isocarboxazid page.
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