Drug interactions
Isoproterenol + Risperidone
Severity: Minor
Isoproterenol and Risperidone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Risperidone's alpha-1 blockade can cause vasodilation and orthostatic hypotension, and isoproterenol also produces vasodilation and can lower diastolic pressure. Isoproterenol-induced tachycardia may be amplified by risperidone-related reflex tachycardia. The sedation notion in the original entry is not a meaningful interaction.
What this interaction means in plain words
Isoproterenol and Risperidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Isoproterenol belongs to Respiratory; Risperidone belongs to Central Nervous System.
Why it happens
Additive hemodynamic effects from alpha-1 blockade (risperidone) and beta-agonist vasodilation (isoproterenol); no established pharmacokinetic interaction.
What to do
Monitor blood pressure and heart rate when isoproterenol is given to a patient on risperidone, and titrate isoproterenol to effect.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Risperidone
- Ibutilide + Risperidone Contraindicated
- Risperidone + Vandetanib Contraindicated
- Adagrasib + Risperidone Major
- Amiodarone + Risperidone Major
- Amisulpride + Risperidone Major
- Amoxapine + Risperidone Major
Other interactions of Isoproterenol
Frequently asked questions
Can I take Isoproterenol with Risperidone?
MediHelp rates the interaction as minor. Isoproterenol and Risperidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Risperidone's alpha-1 blockade can cause vasodilation and orthostatic hypotension, and isoproterenol also produces vasodilation and can lower diastolic pressure. Isoproterenol-induced tachycardia may be amplified by risperidone-related reflex tachycardia. The sedation notion in the original entry is not a meaningful interaction.
How serious is the interaction between Isoproterenol and Risperidone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate when isoproterenol is given to a patient on risperidone, and titrate isoproterenol to effect.
What other medicines interact with Risperidone?
MediHelp also lists interactions of Risperidone with, for example, Ibutilide, Vandetanib, Adagrasib. The full list is on the Risperidone page.
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