Drug interactions
Isotretinoin + Moxifloxacin
Severity: Minor
Isotretinoin and Moxifloxacin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs can cause photosensitivity, so combined use may increase the risk of sunburn-like skin reactions after ultraviolet exposure. Fluoroquinolones and isotretinoin have also each been linked to tendon problems and intracranial hypertension is a concern with isotretinoin plus tetracyclines rather than quinolones.
What this interaction means in plain words
Isotretinoin and Moxifloxacin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Isotretinoin belongs to Dermatology; Moxifloxacin belongs to Anti Bacterial.
Why it happens
Additive photosensitizing effects of the two drugs.
What to do
Counsel patients to use broad-spectrum sunscreen and protective clothing and avoid tanning and prolonged sun exposure during co-therapy.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Moxifloxacin
- Amiodarone + Moxifloxacin Contraindicated
- Arsenic trioxide + Moxifloxacin Contraindicated
- Disopyramide + Moxifloxacin Contraindicated
- Dofetilide + Moxifloxacin Contraindicated
- Dronedarone + Moxifloxacin Contraindicated
- Droperidol + Moxifloxacin Contraindicated
Other interactions of Isotretinoin
- Demeclocycline + Isotretinoin Contraindicated
- Isotretinoin + Minocycline Contraindicated
- Isotretinoin + Oxytetracycline Contraindicated
- Isotretinoin + Palovarotene Contraindicated
- Aminolevulinic acid + Isotretinoin Major
- Doxycycline + Isotretinoin Major
Frequently asked questions
Can I take Isotretinoin with Moxifloxacin?
MediHelp rates the interaction as minor. Isotretinoin and Moxifloxacin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both drugs can cause photosensitivity, so combined use may increase the risk of sunburn-like skin reactions after ultraviolet exposure. Fluoroquinolones and isotretinoin have also each been linked to tendon problems and intracranial hypertension is a concern with isotretinoin plus tetracyclines rather than quinolones.
How serious is the interaction between Isotretinoin and Moxifloxacin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients to use broad-spectrum sunscreen and protective clothing and avoid tanning and prolonged sun exposure during co-therapy.
What other medicines interact with Moxifloxacin?
MediHelp also lists interactions of Moxifloxacin with, for example, Amiodarone, Arsenic trioxide, Disopyramide. The full list is on the Moxifloxacin page.
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