Drug interactions
Ixekizumab + Pneumococcal vaccine 13-valent
Severity: Minor
Ixekizumab and Pneumococcal vaccine 13-valent: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ixekizumab is an IL-17A antagonist, and studies in psoriasis suggest that patients can still mount adequate responses to non-live vaccines such as pneumococcal conjugate vaccine. The interaction is therefore of limited clinical importance, though immunisation before starting therapy is still preferable.
What this interaction means in plain words
Ixekizumab and Pneumococcal vaccine 13-valent have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ixekizumab belongs to Miscellaneous; Pneumococcal vaccine 13-valent belongs to Miscellaneous.
Why it happens
IL-17A blockade could theoretically blunt immune responses, but vaccine responses appear largely preserved.
What to do
Complete age-appropriate vaccinations before starting ixekizumab where practical. Non-live vaccines may still be given during treatment.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Pneumococcal vaccine 13-valent
- Adalimumab + Pneumococcal vaccine 13-valent Moderate
- Alefacept + Pneumococcal vaccine 13-valent Moderate
- Anakinra + Pneumococcal vaccine 13-valent Moderate
- Anti-thymocyte + Pneumococcal vaccine 13-valent Moderate
- Antithymocyte globulin equine + Pneumococcal vaccine 13-valent Moderate
- Antithymocyte globulin rabbit + Pneumococcal vaccine 13-valent Moderate
Other interactions of Ixekizumab
- Ixekizumab + Measles mumps and rubella vaccine Major
- Ixekizumab + Upadacitinib Major
- Ifosfamide + Ixekizumab Moderate
- Ixekizumab + Lomustine Moderate
- Carbamazepine + Ixekizumab Minor
- Cyclosporin + Ixekizumab Minor
Frequently asked questions
Can I take Ixekizumab with Pneumococcal vaccine 13-valent?
MediHelp rates the interaction as minor. Ixekizumab and Pneumococcal vaccine 13-valent have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ixekizumab is an IL-17A antagonist, and studies in psoriasis suggest that patients can still mount adequate responses to non-live vaccines such as pneumococcal conjugate vaccine. The interaction is therefore of limited clinical importance, though immunisation before starting therapy is still preferable.
How serious is the interaction between Ixekizumab and Pneumococcal vaccine 13-valent?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Complete age-appropriate vaccinations before starting ixekizumab where practical. Non-live vaccines may still be given during treatment.
What other medicines interact with Pneumococcal vaccine 13-valent?
MediHelp also lists interactions of Pneumococcal vaccine 13-valent with, for example, Adalimumab, Alefacept, Anakinra. The full list is on the Pneumococcal vaccine 13-valent page.
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