Drug interactions
Lanreotide + Metformin-pioglitazone
Severity: Moderate
Lanreotide and Metformin-pioglitazone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lanreotide suppresses insulin, glucagon and growth hormone secretion, which can cause either hyperglycemia or hypoglycemia. This may change the glucose control achieved with metformin and pioglitazone.
What this interaction means in plain words
Lanreotide and Metformin-pioglitazone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Lanreotide belongs to Endocrine; Metformin-pioglitazone belongs to Endocrine.
Why it happens
Somatostatin analog inhibition of insulin and counter-regulatory hormone secretion alters glycemia.
What to do
Monitor blood glucose when starting, changing or stopping lanreotide, and adjust antidiabetic doses accordingly.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Metformin-pioglitazone
Other interactions of Lanreotide
- Lanreotide + Quinidine Major
- Alogliptin-metformin + Lanreotide Moderate
- Canagliflozin-metformin + Lanreotide Moderate
- Cyclosporin + Lanreotide Moderate
- Dapagliflozin-metformin + Lanreotide Moderate
- Empagliflozin-metformin + Lanreotide Moderate
Frequently asked questions
Can I take Lanreotide with Metformin-pioglitazone?
MediHelp rates the interaction as moderate. Lanreotide and Metformin-pioglitazone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lanreotide suppresses insulin, glucagon and growth hormone secretion, which can cause either hyperglycemia or hypoglycemia. This may change the glucose control achieved with metformin and pioglitazone.
How serious is the interaction between Lanreotide and Metformin-pioglitazone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when starting, changing or stopping lanreotide, and adjust antidiabetic doses accordingly.
What other medicines interact with Metformin-pioglitazone?
MediHelp also lists interactions of Metformin-pioglitazone with, for example, Contrast media, Diatrizoate meglumine / diatrizoate, Diatrizoate. The full list is on the Metformin-pioglitazone page.
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