Drug interactions
Lanreotide + Nateglinide
Severity: Moderate
Lanreotide and Nateglinide: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lanreotide suppresses insulin, glucagon and growth hormone secretion, so it may either raise or lower blood glucose. Glycemic control in patients taking nateglinide may therefore become unpredictable.
What this interaction means in plain words
Lanreotide and Nateglinide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Lanreotide belongs to Endocrine; Nateglinide belongs to Endocrine.
Why it happens
Somatostatin analogue inhibition of insulin and counter-regulatory hormone secretion alters nateglinide's glycemic effect.
What to do
Monitor blood glucose when lanreotide is started or the dose is changed. Adjust the nateglinide dose according to the glucose trend.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Nateglinide
- Albiglutide + Nateglinide Moderate
- Alogliptin-metformin + Nateglinide Moderate
- Alogliptin-pioglitazone + Nateglinide Moderate
- Alogliptin + Nateglinide Moderate
- Alpelisib + Nateglinide Moderate
- Amiodarone + Nateglinide Moderate
Other interactions of Lanreotide
- Lanreotide + Quinidine Major
- Alogliptin-metformin + Lanreotide Moderate
- Canagliflozin-metformin + Lanreotide Moderate
- Cyclosporin + Lanreotide Moderate
- Dapagliflozin-metformin + Lanreotide Moderate
- Empagliflozin-metformin + Lanreotide Moderate
Frequently asked questions
Can I take Lanreotide with Nateglinide?
MediHelp rates the interaction as moderate. Lanreotide and Nateglinide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lanreotide suppresses insulin, glucagon and growth hormone secretion, so it may either raise or lower blood glucose. Glycemic control in patients taking nateglinide may therefore become unpredictable.
How serious is the interaction between Lanreotide and Nateglinide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when lanreotide is started or the dose is changed. Adjust the nateglinide dose according to the glucose trend.
What other medicines interact with Nateglinide?
MediHelp also lists interactions of Nateglinide with, for example, Albiglutide, Alogliptin-metformin, Alogliptin-pioglitazone. The full list is on the Nateglinide page.
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