Drug interactions
Lanthanum carbonate + Minocycline
Severity: Moderate
Lanthanum carbonate and Minocycline: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lanthanum is a polyvalent cation that can bind tetracyclines in the gut, reducing minocycline absorption and potentially antibiotic effect.
What this interaction means in plain words
Lanthanum carbonate and Minocycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Lanthanum carbonate belongs to Miscellaneous; Minocycline belongs to Anti Bacterial.
Why it happens
Chelation of minocycline by lanthanum in the gastrointestinal tract reduces absorption.
What to do
Give oral minocycline at least 2 hours before or after lanthanum carbonate. Monitor clinical response to the antibiotic.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Minocycline
- Acitretin + Minocycline Contraindicated
- Isotretinoin + Minocycline Contraindicated
- Cholera vaccine + Minocycline Major
- Methoxyflurane + Minocycline Major
- Minocycline + Palovarotene Major
- Minocycline + Pexidartinib Major
Other interactions of Lanthanum carbonate
Frequently asked questions
Can I take Lanthanum carbonate with Minocycline?
MediHelp rates the interaction as moderate. Lanthanum carbonate and Minocycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lanthanum is a polyvalent cation that can bind tetracyclines in the gut, reducing minocycline absorption and potentially antibiotic effect.
How serious is the interaction between Lanthanum carbonate and Minocycline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give oral minocycline at least 2 hours before or after lanthanum carbonate. Monitor clinical response to the antibiotic.
What other medicines interact with Minocycline?
MediHelp also lists interactions of Minocycline with, for example, Acitretin, Isotretinoin, Cholera vaccine. The full list is on the Minocycline page.
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