Drug interactions
Lanthanum carbonate + Tetracycline
Severity: Moderate
Lanthanum carbonate and Tetracycline: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lanthanum carbonate releases polyvalent cations in the gut that bind oral tetracycline. This reduces tetracycline absorption and may lead to subtherapeutic antibiotic levels and treatment failure.
What this interaction means in plain words
Lanthanum carbonate and Tetracycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Lanthanum carbonate belongs to Miscellaneous; Tetracycline belongs to Anti Bacterial.
Why it happens
Chelation of tetracycline by lanthanum cations in the gastrointestinal tract reduces absorption.
What to do
Give oral tetracycline at least 2 hours before or after lanthanum carbonate. Monitor clinical response to the antibiotic.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Tetracycline
- Acitretin + Tetracycline Contraindicated
- Methoxyflurane + Tetracycline Contraindicated
- Isotretinoin + Tetracycline Major
- Palovarotene + Tetracycline Major
- Strontium ranelate + Tetracycline Major
- Tetracycline + Tretinoin Major
Other interactions of Lanthanum carbonate
Frequently asked questions
Can I take Lanthanum carbonate with Tetracycline?
MediHelp rates the interaction as moderate. Lanthanum carbonate and Tetracycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lanthanum carbonate releases polyvalent cations in the gut that bind oral tetracycline. This reduces tetracycline absorption and may lead to subtherapeutic antibiotic levels and treatment failure.
How serious is the interaction between Lanthanum carbonate and Tetracycline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give oral tetracycline at least 2 hours before or after lanthanum carbonate. Monitor clinical response to the antibiotic.
What other medicines interact with Tetracycline?
MediHelp also lists interactions of Tetracycline with, for example, Acitretin, Methoxyflurane, Isotretinoin. The full list is on the Tetracycline page.
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