Drug interactions
Lanthanum carbonate + Trandolapril
Severity: Minor
Lanthanum carbonate and Trandolapril: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lanthanum is a cation that binds drugs in the gut and may reduce the absorption of some oral medicines. This could lower trandolapril exposure and weaken blood pressure control. The effect is predicted rather than well documented for this ACE inhibitor.
What this interaction means in plain words
Lanthanum carbonate and Trandolapril have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Lanthanum carbonate belongs to Miscellaneous; Trandolapril belongs to Cardiovascular.
Why it happens
Binding of trandolapril by lanthanum cations in the gastrointestinal tract may reduce absorption.
What to do
Take trandolapril at least 2 hours before or after lanthanum carbonate. Monitor blood pressure if dosing times cannot be separated.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Trandolapril
- Aliskiren + Trandolapril Contraindicated
- Protein a column + Trandolapril Contraindicated
- Sacubitril / valsartan + Trandolapril Contraindicated
- Sacubitril-valsartan + Trandolapril Contraindicated
- Aldesleukin + Trandolapril Major
- Amifostine + Trandolapril Major
Other interactions of Lanthanum carbonate
Frequently asked questions
Can I take Lanthanum carbonate with Trandolapril?
MediHelp rates the interaction as minor. Lanthanum carbonate and Trandolapril have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Lanthanum is a cation that binds drugs in the gut and may reduce the absorption of some oral medicines. This could lower trandolapril exposure and weaken blood pressure control. The effect is predicted rather than well documented for this ACE inhibitor.
How serious is the interaction between Lanthanum carbonate and Trandolapril?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take trandolapril at least 2 hours before or after lanthanum carbonate. Monitor blood pressure if dosing times cannot be separated.
What other medicines interact with Trandolapril?
MediHelp also lists interactions of Trandolapril with, for example, Aliskiren, Protein a column, Sacubitril / valsartan. The full list is on the Trandolapril page.
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