Drug interactions
Lemborexant + Micafungin
Severity: Minor
Lemborexant and Micafungin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Weak CYP3A4 inhibitors raise lemborexant exposure, increasing the risk of next-day somnolence and impaired alertness. Micafungin's CYP3A4 inhibition is weak, so the effect is likely small.
What this interaction means in plain words
Lemborexant and Micafungin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Lemborexant belongs to Central Nervous System; Micafungin belongs to Anti Fungals.
Why it happens
Weak CYP3A4 inhibition by micafungin reduces lemborexant clearance.
What to do
Follow labeling for weak CYP3A4 inhibitors by limiting lemborexant to the lower recommended nightly dose, and counsel on next-day drowsiness.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Micafungin
- Lomitapide + Micafungin Moderate
- Micafungin + Saccharomyces boulardii Moderate
- Micafungin + Sirolimus Moderate
- Avapritinib + Micafungin Minor
- Finerenone + Micafungin Minor
- Isavuconazonium + Micafungin Minor
Other interactions of Lemborexant
Frequently asked questions
Can I take Lemborexant with Micafungin?
MediHelp rates the interaction as minor. Lemborexant and Micafungin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Weak CYP3A4 inhibitors raise lemborexant exposure, increasing the risk of next-day somnolence and impaired alertness. Micafungin's CYP3A4 inhibition is weak, so the effect is likely small.
How serious is the interaction between Lemborexant and Micafungin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Follow labeling for weak CYP3A4 inhibitors by limiting lemborexant to the lower recommended nightly dose, and counsel on next-day drowsiness.
What other medicines interact with Micafungin?
MediHelp also lists interactions of Micafungin with, for example, Lomitapide, Saccharomyces boulardii, Sirolimus. The full list is on the Micafungin page.
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