Drug interactions
Levetiracetam + Mirtazapine
Severity: Minor
Levetiracetam and Mirtazapine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs can cause somnolence and dizziness, so together they may increase drowsiness and impair concentration. Levetiracetam can also cause mood and behavioral changes that may complicate depression treatment.
What this interaction means in plain words
Levetiracetam and Mirtazapine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Levetiracetam belongs to Central Nervous System; Mirtazapine belongs to Central Nervous System.
Why it happens
Additive CNS depressant effects.
What to do
Counsel about drowsiness and driving, especially at initiation or dose increases. Monitor mood and behavior in patients being treated for depression.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Mirtazapine
- Isocarboxazid + Mirtazapine Contraindicated
- Mirtazapine + Phenelzine Contraindicated
- Mirtazapine + Pimozide Contraindicated
- Mirtazapine + Procarbazine Contraindicated
- Mirtazapine + Rasagiline Contraindicated
- Mirtazapine + Selegiline Contraindicated
Other interactions of Levetiracetam
Frequently asked questions
Can I take Levetiracetam with Mirtazapine?
MediHelp rates the interaction as minor. Levetiracetam and Mirtazapine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both drugs can cause somnolence and dizziness, so together they may increase drowsiness and impair concentration. Levetiracetam can also cause mood and behavioral changes that may complicate depression treatment.
How serious is the interaction between Levetiracetam and Mirtazapine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel about drowsiness and driving, especially at initiation or dose increases. Monitor mood and behavior in patients being treated for depression.
What other medicines interact with Mirtazapine?
MediHelp also lists interactions of Mirtazapine with, for example, Isocarboxazid, Phenelzine, Pimozide. The full list is on the Mirtazapine page.
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