Drug interactions
Levetiracetam + Opicapone
Severity: Minor
Levetiracetam and Opicapone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Opicapone is a COMT inhibitor used with levodopa, and its main effects are dyskinesia and, less commonly, somnolence. There is no established meaningful sedative interaction with levetiracetam.
What this interaction means in plain words
Levetiracetam and Opicapone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Levetiracetam belongs to Central Nervous System; Opicapone belongs to Central Nervous System.
Why it happens
No established mechanism; any effect would be a minor additive somnolence.
What to do
No routine action is needed; monitor for drowsiness if symptoms appear.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Levetiracetam
Other interactions of Opicapone
- Isocarboxazid + Opicapone Contraindicated
- Opicapone + Phenelzine Contraindicated
- Opicapone + Tranylcypromine Contraindicated
- Adrenaline-articaine + Opicapone Moderate
- Asenapine + Opicapone Moderate
- Dobutamine + Opicapone Moderate
Frequently asked questions
Can I take Levetiracetam with Opicapone?
MediHelp rates the interaction as minor. Levetiracetam and Opicapone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Opicapone is a COMT inhibitor used with levodopa, and its main effects are dyskinesia and, less commonly, somnolence. There is no established meaningful sedative interaction with levetiracetam.
How serious is the interaction between Levetiracetam and Opicapone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed; monitor for drowsiness if symptoms appear.
What other medicines interact with Levetiracetam?
MediHelp also lists interactions of Levetiracetam with, for example, Oliceridine, Opium tincture, Sodium oxybate. The full list is on the Levetiracetam page.
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