Drug interactions
Levetiracetam + Risperidone
Severity: Minor
Levetiracetam and Risperidone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs can cause somnolence, dizziness and psychomotor slowing, and combined use may increase these effects. Levetiracetam can also cause irritability or psychiatric symptoms that may complicate treatment of psychotic illness.
What this interaction means in plain words
Levetiracetam and Risperidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Levetiracetam belongs to Central Nervous System; Risperidone belongs to Central Nervous System.
Why it happens
Additive CNS depressant effects; no significant pharmacokinetic interaction is expected.
What to do
Advise patients about drowsiness and caution with driving. Monitor mental status and behavior after starting or increasing doses.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Risperidone
- Ibutilide + Risperidone Contraindicated
- Risperidone + Vandetanib Contraindicated
- Adagrasib + Risperidone Major
- Amiodarone + Risperidone Major
- Amisulpride + Risperidone Major
- Amoxapine + Risperidone Major
Other interactions of Levetiracetam
Frequently asked questions
Can I take Levetiracetam with Risperidone?
MediHelp rates the interaction as minor. Levetiracetam and Risperidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both drugs can cause somnolence, dizziness and psychomotor slowing, and combined use may increase these effects. Levetiracetam can also cause irritability or psychiatric symptoms that may complicate treatment of psychotic illness.
How serious is the interaction between Levetiracetam and Risperidone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients about drowsiness and caution with driving. Monitor mental status and behavior after starting or increasing doses.
What other medicines interact with Risperidone?
MediHelp also lists interactions of Risperidone with, for example, Ibutilide, Vandetanib, Adagrasib. The full list is on the Risperidone page.
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