Drug interactions
Levofloxacin + Triclabendazole
Severity: Moderate
Levofloxacin and Triclabendazole: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs can prolong the QT interval. Giving them together may increase the likelihood of torsades de pointes, especially in patients with electrolyte abnormalities or heart disease.
What this interaction means in plain words
Levofloxacin and Triclabendazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Levofloxacin belongs to Anti Bacterial; Triclabendazole belongs to Anti Parasitic.
Why it happens
Additive prolongation of cardiac repolarization (QT interval).
What to do
Check an ECG and serum potassium and magnesium before use in patients with cardiac risk factors. Prefer a non-QT-prolonging antibiotic when feasible.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Levofloxacin
- Dronedarone + Levofloxacin Contraindicated
- Ibutilide + Levofloxacin Contraindicated
- Levofloxacin + Thioridazine Contraindicated
- Levofloxacin + Vandetanib Contraindicated
- Levofloxacin + Ziprasidone Contraindicated
- Adagrasib + Levofloxacin Major
Other interactions of Triclabendazole
Frequently asked questions
Can I take Levofloxacin with Triclabendazole?
MediHelp rates the interaction as moderate. Levofloxacin and Triclabendazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs can prolong the QT interval. Giving them together may increase the likelihood of torsades de pointes, especially in patients with electrolyte abnormalities or heart disease.
How serious is the interaction between Levofloxacin and Triclabendazole?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check an ECG and serum potassium and magnesium before use in patients with cardiac risk factors. Prefer a non-QT-prolonging antibiotic when feasible.
What other medicines interact with Levofloxacin?
MediHelp also lists interactions of Levofloxacin with, for example, Dronedarone, Ibutilide, Thioridazine. The full list is on the Levofloxacin page.
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