Drug interactions
Liraglutide + Losartan
Severity: Minor
Liraglutide and Losartan: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Angiotensin receptor blockers may slightly improve insulin sensitivity and enhance glucose lowering of antidiabetic drugs. With liraglutide alone the hypoglycemia risk is low, so the effect is usually small.
What this interaction means in plain words
Liraglutide and Losartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Liraglutide belongs to Endocrine; Losartan belongs to Cardiovascular.
Why it happens
Possible improvement in insulin sensitivity from angiotensin receptor blockade adds to the glucose lowering effects of liraglutide.
What to do
Monitor glycemic control when losartan is started or stopped; no dose change is usually required.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Losartan
- Aliskiren + Losartan Contraindicated
- Losartan + Sparsentan Contraindicated
- Amifostine + Losartan Major
- Amiloride + Losartan Major
- Amlodipine-benazepril + Losartan Major
- Amlodipine-hydrochlorothiazide-valsartan + Losartan Major
Other interactions of Liraglutide
Frequently asked questions
Can I take Liraglutide with Losartan?
MediHelp rates the interaction as minor. Liraglutide and Losartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Angiotensin receptor blockers may slightly improve insulin sensitivity and enhance glucose lowering of antidiabetic drugs. With liraglutide alone the hypoglycemia risk is low, so the effect is usually small.
How serious is the interaction between Liraglutide and Losartan?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor glycemic control when losartan is started or stopped; no dose change is usually required.
What other medicines interact with Losartan?
MediHelp also lists interactions of Losartan with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Losartan page.
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