Drug interactions
Liraglutide + Tipranavir
Severity: Moderate
Liraglutide and Tipranavir: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tipranavir, a protease inhibitor, can be associated with insulin resistance and hyperglycemia, potentially counteracting liraglutide's glucose-lowering effect.
What this interaction means in plain words
Liraglutide and Tipranavir can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Liraglutide belongs to Endocrine; Tipranavir belongs to Anti Virals.
Why it happens
Pharmacodynamic antagonism via protease inhibitor-induced insulin resistance.
What to do
Monitor glucose and HbA1c after starting or changing tipranavir. Intensify antidiabetic therapy as needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Liraglutide
Other interactions of Tipranavir
- Alfuzosin + Tipranavir Contraindicated
- Amiodarone + Tipranavir Contraindicated
- Atorvastatin + Tipranavir Contraindicated
- Avanafil + Tipranavir Contraindicated
- Cisapride + Tipranavir Contraindicated
- Colchicine + Tipranavir Contraindicated
Frequently asked questions
Can I take Liraglutide with Tipranavir?
MediHelp rates the interaction as moderate. Liraglutide and Tipranavir can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Tipranavir, a protease inhibitor, can be associated with insulin resistance and hyperglycemia, potentially counteracting liraglutide's glucose-lowering effect.
How serious is the interaction between Liraglutide and Tipranavir?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor glucose and HbA1c after starting or changing tipranavir. Intensify antidiabetic therapy as needed.
What other medicines interact with Liraglutide?
MediHelp also lists interactions of Liraglutide with, for example, Insulin degludec-liraglutide, Insulin glargine-lixisenatide, Alogliptin-metformin. The full list is on the Liraglutide page.
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