Drug interactions
Lornoxicam + Succinylcholine
Severity: Minor
Lornoxicam and Succinylcholine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
NSAIDs such as lornoxicam may raise serum potassium, particularly in renal impairment, and succinylcholine causes a transient rise. The combined effect is usually small in patients with normal kidney function. Risk is greater in those with kidney disease or other hyperkalemic drugs.
What this interaction means in plain words
Lornoxicam and Succinylcholine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Lornoxicam belongs to Musculoskeletal; Succinylcholine belongs to Musculoskeletal.
Why it happens
NSAIDs reduce renal potassium excretion through prostaglandin inhibition, adding to succinylcholine-induced potassium release.
What to do
Check potassium and renal function in at-risk patients before using succinylcholine. Consider an alternative neuromuscular blocker if hyperkalemia is present.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Succinylcholine
Other interactions of Lornoxicam
Frequently asked questions
Can I take Lornoxicam with Succinylcholine?
MediHelp rates the interaction as minor. Lornoxicam and Succinylcholine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. NSAIDs such as lornoxicam may raise serum potassium, particularly in renal impairment, and succinylcholine causes a transient rise. The combined effect is usually small in patients with normal kidney function. Risk is greater in those with kidney disease or other hyperkalemic drugs.
How serious is the interaction between Lornoxicam and Succinylcholine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check potassium and renal function in at-risk patients before using succinylcholine. Consider an alternative neuromuscular blocker if hyperkalemia is present.
What other medicines interact with Succinylcholine?
MediHelp also lists interactions of Succinylcholine with, for example, Amikacin, Bacitracin-neomycin-polymyxin, Capreomycin. The full list is on the Succinylcholine page.
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