Drug interactions
Lornoxicam + Torsemide
Severity: Moderate
Lornoxicam and Torsemide: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
NSAIDs such as lornoxicam can blunt the diuretic and antihypertensive effect of loop diuretics and raise the risk of acute kidney injury, especially in dehydrated or heart failure patients. NSAIDs may also cause sodium and fluid retention and raise potassium.
What this interaction means in plain words
Lornoxicam and Torsemide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Lornoxicam belongs to Musculoskeletal; Torsemide belongs to Cardiovascular.
Why it happens
NSAID inhibition of renal prostaglandin synthesis reduces renal blood flow and sodium excretion, opposing loop diuretic action.
What to do
Avoid prolonged combined use where possible; if needed, use the lowest NSAID dose for the shortest time and monitor weight, blood pressure, creatinine and potassium.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Torsemide
Other interactions of Lornoxicam
Frequently asked questions
Can I take Lornoxicam with Torsemide?
MediHelp rates the interaction as moderate. Lornoxicam and Torsemide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. NSAIDs such as lornoxicam can blunt the diuretic and antihypertensive effect of loop diuretics and raise the risk of acute kidney injury, especially in dehydrated or heart failure patients. NSAIDs may also cause sodium and fluid retention and raise potassium.
How serious is the interaction between Lornoxicam and Torsemide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid prolonged combined use where possible; if needed, use the lowest NSAID dose for the shortest time and monitor weight, blood pressure, creatinine and potassium.
What other medicines interact with Torsemide?
MediHelp also lists interactions of Torsemide with, for example, Amikacin, Amiodarone, Carbenoxolone. The full list is on the Torsemide page.
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