Drug interactions
Lovastatin + Pomalidomide
Severity: Minor
Lovastatin and Pomalidomide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Pomalidomide is a P-gp substrate, but lovastatin is not a clinically important P-gp inhibitor, so no meaningful change in pomalidomide exposure is expected. No significant clinical interaction is established.
What this interaction means in plain words
Lovastatin and Pomalidomide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Lovastatin belongs to Cardiovascular; Pomalidomide belongs to Miscellaneous.
Why it happens
Theoretical weak P-gp interaction; not established as clinically relevant.
What to do
No dose adjustment is needed. Monitor routinely for pomalidomide adverse effects.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Lovastatin
- Atazanavir + Lovastatin Contraindicated
- Clarithromycin + Lovastatin Contraindicated
- Cobicistat + Lovastatin Contraindicated
- Conivaptan + Lovastatin Contraindicated
- Darunavir + Lovastatin Contraindicated
- Elvitegravir / cobicistat / emtricitabine / tenofovir df + Lovastatin Contraindicated
Other interactions of Pomalidomide
- Deferiprone + Pomalidomide Major
- Ethinyl estradiol-drospirenone + Pomalidomide Major
- Fluvoxamine + Pomalidomide Major
- Apalutamide + Pomalidomide Moderate
- Brivaracetam + Pomalidomide Moderate
- Carbamazepine + Pomalidomide Moderate
Frequently asked questions
Can I take Lovastatin with Pomalidomide?
MediHelp rates the interaction as minor. Lovastatin and Pomalidomide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Pomalidomide is a P-gp substrate, but lovastatin is not a clinically important P-gp inhibitor, so no meaningful change in pomalidomide exposure is expected. No significant clinical interaction is established.
How serious is the interaction between Lovastatin and Pomalidomide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is needed. Monitor routinely for pomalidomide adverse effects.
What other medicines interact with Lovastatin?
MediHelp also lists interactions of Lovastatin with, for example, Atazanavir, Clarithromycin, Cobicistat. The full list is on the Lovastatin page.
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