Drug interactions
Macimorelin + Moxifloxacin
Severity: Major
Macimorelin and Moxifloxacin: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Macimorelin modestly lengthens the QT interval, and moxifloxacin adds to this effect. The combination may raise the risk of torsades de pointes during the diagnostic test.
What this interaction means in plain words
Macimorelin and Moxifloxacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Macimorelin belongs to Endocrine; Moxifloxacin belongs to Anti Bacterial.
Why it happens
Additive pharmacodynamic QT prolongation.
What to do
Postpone macimorelin testing until moxifloxacin has been stopped and cleared. Otherwise use an alternative diagnostic approach.
What to ask your pharmacist
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Other interactions of Moxifloxacin
- Amiodarone + Moxifloxacin Contraindicated
- Arsenic trioxide + Moxifloxacin Contraindicated
- Disopyramide + Moxifloxacin Contraindicated
- Dofetilide + Moxifloxacin Contraindicated
- Dronedarone + Moxifloxacin Contraindicated
- Droperidol + Moxifloxacin Contraindicated
Other interactions of Macimorelin
Frequently asked questions
Can I take Macimorelin with Moxifloxacin?
MediHelp rates the interaction as major. Macimorelin and Moxifloxacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Macimorelin modestly lengthens the QT interval, and moxifloxacin adds to this effect. The combination may raise the risk of torsades de pointes during the diagnostic test.
How serious is the interaction between Macimorelin and Moxifloxacin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Postpone macimorelin testing until moxifloxacin has been stopped and cleared. Otherwise use an alternative diagnostic approach.
What other medicines interact with Moxifloxacin?
MediHelp also lists interactions of Moxifloxacin with, for example, Amiodarone, Arsenic trioxide, Disopyramide. The full list is on the Moxifloxacin page.
Full monographs, dosing and an interaction checker in the MediHelp app
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