Drug interactions
Maraviroc + Ramipril
Severity: Moderate
Maraviroc and Ramipril: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Maraviroc can cause postural hypotension, and this may add to the blood pressure lowering effect of ramipril. Dizziness and falls are the main concerns, especially in patients with renal impairment or those taking other antihypertensives.
What this interaction means in plain words
Maraviroc and Ramipril can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Maraviroc belongs to Anti Virals; Ramipril belongs to Cardiovascular.
Why it happens
Additive hypotensive effects through pharmacodynamic synergism.
What to do
Monitor for orthostatic symptoms and blood pressure when maraviroc is started, and advise patients to rise slowly. Reduce the ramipril dose if hypotension develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ramipril
- Aliskiren + Ramipril Contraindicated
- Protein a column + Ramipril Contraindicated
- Ramipril + Sacubitril / valsartan Contraindicated
- Ramipril + Sacubitril-valsartan Contraindicated
- Amifostine + Ramipril Major
- Amiloride + Ramipril Major
Other interactions of Maraviroc
- Amobarbital + Maraviroc Major
- Apalutamide + Maraviroc Major
- Carbamazepine + Maraviroc Major
- Clarithromycin + Maraviroc Major
- Efavirenz + Maraviroc Major
- Enzalutamide + Maraviroc Major
Frequently asked questions
Can I take Maraviroc with Ramipril?
MediHelp rates the interaction as moderate. Maraviroc and Ramipril can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Maraviroc can cause postural hypotension, and this may add to the blood pressure lowering effect of ramipril. Dizziness and falls are the main concerns, especially in patients with renal impairment or those taking other antihypertensives.
How serious is the interaction between Maraviroc and Ramipril?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for orthostatic symptoms and blood pressure when maraviroc is started, and advise patients to rise slowly. Reduce the ramipril dose if hypotension develops.
What other medicines interact with Ramipril?
MediHelp also lists interactions of Ramipril with, for example, Aliskiren, Protein a column, Sacubitril / valsartan. The full list is on the Ramipril page.
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