Drug interactions
Maraviroc + Selegiline
Severity: Moderate
Maraviroc and Selegiline: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs can lower blood pressure, and maraviroc is associated with postural hypotension. Together they may increase the risk of dizziness and falls, especially in older patients.
What this interaction means in plain words
Maraviroc and Selegiline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Maraviroc belongs to Anti Virals; Selegiline belongs to Central Nervous System.
Why it happens
Additive hypotensive effects (pharmacodynamic).
What to do
Check orthostatic blood pressure when starting the combination. Counsel patients to rise slowly.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Selegiline
- Amitriptyline + Selegiline Contraindicated
- Amoxapine + Selegiline Contraindicated
- Atomoxetine + Selegiline Contraindicated
- Benzphetamine + Selegiline Contraindicated
- Brimonidine + Selegiline Contraindicated
- Buprenorphine long-acting + Selegiline Contraindicated
Other interactions of Maraviroc
- Amobarbital + Maraviroc Major
- Apalutamide + Maraviroc Major
- Carbamazepine + Maraviroc Major
- Clarithromycin + Maraviroc Major
- Efavirenz + Maraviroc Major
- Enzalutamide + Maraviroc Major
Frequently asked questions
Can I take Maraviroc with Selegiline?
MediHelp rates the interaction as moderate. Maraviroc and Selegiline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs can lower blood pressure, and maraviroc is associated with postural hypotension. Together they may increase the risk of dizziness and falls, especially in older patients.
How serious is the interaction between Maraviroc and Selegiline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check orthostatic blood pressure when starting the combination. Counsel patients to rise slowly.
What other medicines interact with Selegiline?
MediHelp also lists interactions of Selegiline with, for example, Amitriptyline, Amoxapine, Atomoxetine. The full list is on the Selegiline page.
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