Drug interactions
Maraviroc + Tadalafil
Severity: Minor
Maraviroc and Tadalafil: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Maraviroc can cause postural hypotension, and tadalafil's vasodilatory effect may add to it, raising the risk of dizziness and falls.
What this interaction means in plain words
Maraviroc and Tadalafil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Maraviroc belongs to Anti Virals; Tadalafil belongs to Genitourinary.
Why it happens
Additive hypotensive effects; no established pharmacokinetic interaction.
What to do
Monitor for orthostatic symptoms and counsel patients to rise slowly.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Tadalafil
- Amyl nitrite + Tadalafil Contraindicated
- Isosorbide dinitrate + Tadalafil Contraindicated
- Isosorbide mononitrate + Tadalafil Contraindicated
- Nitroglycerin po + Tadalafil Contraindicated
- Nitroglycerin rectal + Tadalafil Contraindicated
- Nitroglycerin sublingual + Tadalafil Contraindicated
Other interactions of Maraviroc
- Amobarbital + Maraviroc Major
- Apalutamide + Maraviroc Major
- Carbamazepine + Maraviroc Major
- Clarithromycin + Maraviroc Major
- Efavirenz + Maraviroc Major
- Enzalutamide + Maraviroc Major
Frequently asked questions
Can I take Maraviroc with Tadalafil?
MediHelp rates the interaction as minor. Maraviroc and Tadalafil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Maraviroc can cause postural hypotension, and tadalafil's vasodilatory effect may add to it, raising the risk of dizziness and falls.
How serious is the interaction between Maraviroc and Tadalafil?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for orthostatic symptoms and counsel patients to rise slowly.
What other medicines interact with Tadalafil?
MediHelp also lists interactions of Tadalafil with, for example, Amyl nitrite, Isosorbide dinitrate, Isosorbide mononitrate. The full list is on the Tadalafil page.
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