Drug interactions
Maraviroc + Timolol
Severity: Minor
Maraviroc and Timolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Maraviroc has been reported to inhibit CYP2D6 in vitro, but a clinically meaningful effect on timolol has not been well established. Any increase in timolol exposure would be expected to be modest.
What this interaction means in plain words
Maraviroc and Timolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Maraviroc belongs to Anti Virals; Timolol belongs to Cardiovascular.
Why it happens
Possible weak CYP2D6 inhibition; the mechanism is not firmly established in clinical studies.
What to do
No routine adjustment is needed. Monitor heart rate and blood pressure when starting maraviroc in patients taking timolol.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Timolol
- Acebutolol + Timolol Major
- Albuterol + Timolol Major
- Aldesleukin + Timolol Major
- Amifostine + Timolol Major
- Amiodarone + Timolol Major
- Arformoterol + Timolol Major
Other interactions of Maraviroc
- Amobarbital + Maraviroc Major
- Apalutamide + Maraviroc Major
- Carbamazepine + Maraviroc Major
- Clarithromycin + Maraviroc Major
- Efavirenz + Maraviroc Major
- Enzalutamide + Maraviroc Major
Frequently asked questions
Can I take Maraviroc with Timolol?
MediHelp rates the interaction as minor. Maraviroc and Timolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Maraviroc has been reported to inhibit CYP2D6 in vitro, but a clinically meaningful effect on timolol has not been well established. Any increase in timolol exposure would be expected to be modest.
How serious is the interaction between Maraviroc and Timolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed. Monitor heart rate and blood pressure when starting maraviroc in patients taking timolol.
What other medicines interact with Timolol?
MediHelp also lists interactions of Timolol with, for example, Acebutolol, Albuterol, Aldesleukin. The full list is on the Timolol page.
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