Drug interactions
Maraviroc + Trandolapril
Severity: Moderate
Maraviroc and Trandolapril: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Maraviroc has been associated with postural hypotension, particularly in patients with renal impairment or taking other blood pressure lowering drugs. Combined with trandolapril the risk of symptomatic hypotension may increase.
What this interaction means in plain words
Maraviroc and Trandolapril can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Maraviroc belongs to Anti Virals; Trandolapril belongs to Cardiovascular.
Why it happens
Additive hypotensive effects; maraviroc can cause postural hypotension through an incompletely defined mechanism.
What to do
Monitor blood pressure and watch for orthostatic symptoms, especially in renal impairment. Counsel patients to rise slowly.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Maraviroc and Trandolapril, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Trandolapril
- Aliskiren + Trandolapril Contraindicated
- Protein a column + Trandolapril Contraindicated
- Sacubitril / valsartan + Trandolapril Contraindicated
- Sacubitril-valsartan + Trandolapril Contraindicated
- Aldesleukin + Trandolapril Major
- Amifostine + Trandolapril Major
Other interactions of Maraviroc
- Amobarbital + Maraviroc Major
- Apalutamide + Maraviroc Major
- Carbamazepine + Maraviroc Major
- Clarithromycin + Maraviroc Major
- Efavirenz + Maraviroc Major
- Enzalutamide + Maraviroc Major
Frequently asked questions
Can I take Maraviroc with Trandolapril?
MediHelp rates the interaction as moderate. Maraviroc and Trandolapril can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Maraviroc has been associated with postural hypotension, particularly in patients with renal impairment or taking other blood pressure lowering drugs. Combined with trandolapril the risk of symptomatic hypotension may increase.
How serious is the interaction between Maraviroc and Trandolapril?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and watch for orthostatic symptoms, especially in renal impairment. Counsel patients to rise slowly.
What other medicines interact with Trandolapril?
MediHelp also lists interactions of Trandolapril with, for example, Aliskiren, Protein a column, Sacubitril / valsartan. The full list is on the Trandolapril page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
