Drug interactions
Mesterolone + Rosiglitazone
Severity: Minor
Mesterolone and Rosiglitazone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Androgens such as mesterolone may improve insulin sensitivity and lower glucose, which could slightly enhance the effect of rosiglitazone. The clinical significance is likely small, but hypoglycemia is theoretically possible.
What this interaction means in plain words
Mesterolone and Rosiglitazone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Mesterolone belongs to Endocrine; Rosiglitazone belongs to Endocrine.
Why it happens
Possible additive improvement in insulin sensitivity; the mechanism is not firmly established.
What to do
Monitor blood glucose when mesterolone is started or stopped. Reduce the antidiabetic dose only if hypoglycemia or low readings appear.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Rosiglitazone
- Insulin aspart protamine / insulin aspart + Rosiglitazone Major
- Insulin aspart-insulin aspart protamine + Rosiglitazone Major
- Insulin aspart + Rosiglitazone Major
- Insulin degludec / insulin aspart + Rosiglitazone Major
- Insulin degludec-insulin aspart + Rosiglitazone Major
- Insulin degludec-liraglutide + Rosiglitazone Major
Other interactions of Mesterolone
Frequently asked questions
Can I take Mesterolone with Rosiglitazone?
MediHelp rates the interaction as minor. Mesterolone and Rosiglitazone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Androgens such as mesterolone may improve insulin sensitivity and lower glucose, which could slightly enhance the effect of rosiglitazone. The clinical significance is likely small, but hypoglycemia is theoretically possible.
How serious is the interaction between Mesterolone and Rosiglitazone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when mesterolone is started or stopped. Reduce the antidiabetic dose only if hypoglycemia or low readings appear.
What other medicines interact with Rosiglitazone?
MediHelp also lists interactions of Rosiglitazone with, for example, Insulin aspart protamine / insulin aspart, Insulin aspart-insulin aspart protamine, Insulin aspart. The full list is on the Rosiglitazone page.
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