Drug interactions
Metformin-repaglinide + Vilazodone
Severity: Minor
Metformin-repaglinide and Vilazodone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Serotonergic antidepressants may cause changes in glucose control, occasionally hypoglycemia, in patients on antidiabetic drugs. The effect is unpredictable and generally small.
What this interaction means in plain words
Metformin-repaglinide and Vilazodone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Metformin-repaglinide belongs to Endocrine; Vilazodone belongs to Central Nervous System.
Why it happens
Possible additive glucose lowering via serotonergic effects on insulin sensitivity; not well established.
What to do
Monitor blood glucose when vilazodone is started or stopped.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Metformin-repaglinide
Other interactions of Vilazodone
- Isocarboxazid + Vilazodone Contraindicated
- Methylene blue + Vilazodone Contraindicated
- Phenelzine + Vilazodone Contraindicated
- Rasagiline + Vilazodone Contraindicated
- Selegiline transdermal + Vilazodone Contraindicated
- Selegiline + Vilazodone Contraindicated
Frequently asked questions
Can I take Metformin-repaglinide with Vilazodone?
MediHelp rates the interaction as minor. Metformin-repaglinide and Vilazodone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Serotonergic antidepressants may cause changes in glucose control, occasionally hypoglycemia, in patients on antidiabetic drugs. The effect is unpredictable and generally small.
How serious is the interaction between Metformin-repaglinide and Vilazodone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when vilazodone is started or stopped.
What other medicines interact with Metformin-repaglinide?
MediHelp also lists interactions of Metformin-repaglinide with, for example, Gemfibrozil, Apalutamide, Clarithromycin. The full list is on the Metformin-repaglinide page.
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