Drug interactions
Methamphetamine + Oxytocin
Severity: Moderate
Methamphetamine and Oxytocin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oxytocin can cause hypotension or tachycardia when given in obstetric settings, while methamphetamine and other sympathomimetics raise blood pressure. Their pressor effects may combine unpredictably, and a hypertensive episode is possible in vulnerable patients.
What this interaction means in plain words
Methamphetamine and Oxytocin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Methamphetamine belongs to Central Nervous System; Oxytocin belongs to Endocrine.
Why it happens
Additive pharmacodynamic cardiovascular effects; sympathomimetic vasopressor action plus oxytocin hemodynamic effects.
What to do
Monitor blood pressure and heart rate continuously during oxytocin administration in patients using methamphetamine. Treat hypertension promptly.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Methamphetamine
- Isocarboxazid + Methamphetamine Contraindicated
- Linezolid + Methamphetamine Contraindicated
- Methamphetamine + Phenelzine Contraindicated
- Methamphetamine + Procarbazine Contraindicated
- Methamphetamine + Rasagiline Contraindicated
- Methamphetamine + Safinamide Contraindicated
Other interactions of Oxytocin
- Carboprost tromethamine + Oxytocin Major
- Dinoprostone + Oxytocin Major
- Ephedrine + Oxytocin Major
- Fexinidazole + Oxytocin Major
- Givinostat + Oxytocin Major
- Misoprostol + Oxytocin Major
Frequently asked questions
Can I take Methamphetamine with Oxytocin?
MediHelp rates the interaction as moderate. Methamphetamine and Oxytocin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oxytocin can cause hypotension or tachycardia when given in obstetric settings, while methamphetamine and other sympathomimetics raise blood pressure. Their pressor effects may combine unpredictably, and a hypertensive episode is possible in vulnerable patients.
How serious is the interaction between Methamphetamine and Oxytocin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate continuously during oxytocin administration in patients using methamphetamine. Treat hypertension promptly.
What other medicines interact with Methamphetamine?
MediHelp also lists interactions of Methamphetamine with, for example, Isocarboxazid, Linezolid, Phenelzine. The full list is on the Methamphetamine page.
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