Drug interactions
Metoclopramide + Oxcarbazepine
Severity: Minor
Metoclopramide and Oxcarbazepine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs can cause dizziness, somnolence and other CNS effects. Combined use may increase these effects, though no strong pharmacokinetic interaction is established.
What this interaction means in plain words
Metoclopramide and Oxcarbazepine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Metoclopramide belongs to Gastrointestinal Tract; Oxcarbazepine belongs to Central Nervous System.
Why it happens
Additive CNS effects; no established pharmacokinetic mechanism.
What to do
Counsel on drowsiness and dizziness, and monitor for neurological adverse effects after starting.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Metoclopramide
Other interactions of Oxcarbazepine
- Cabotegravir + Oxcarbazepine Contraindicated
- Oxcarbazepine + Rilpivirine Contraindicated
- Artemether / lumefantrine + Oxcarbazepine Major
- Atazanavir + Oxcarbazepine Major
- Benzhydrocodone / acetaminophen + Oxcarbazepine Major
- Bictegravir + Oxcarbazepine Major
Frequently asked questions
Can I take Metoclopramide with Oxcarbazepine?
MediHelp rates the interaction as minor. Metoclopramide and Oxcarbazepine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both drugs can cause dizziness, somnolence and other CNS effects. Combined use may increase these effects, though no strong pharmacokinetic interaction is established.
How serious is the interaction between Metoclopramide and Oxcarbazepine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel on drowsiness and dizziness, and monitor for neurological adverse effects after starting.
What other medicines interact with Metoclopramide?
MediHelp also lists interactions of Metoclopramide with, for example, Amantadine, Amoxapine, Antipsychotics (e.g., haloperidol). The full list is on the Metoclopramide page.
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