Drug interactions
Micafungin + Voclosporin
Severity: Minor
Micafungin and Voclosporin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Voclosporin is nephrotoxic in a dose-related manner. Micafungin has little direct nephrotoxicity, so additive harm is theoretical.
What this interaction means in plain words
Micafungin and Voclosporin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Micafungin belongs to Anti Fungals; Voclosporin belongs to Miscellaneous.
Why it happens
No established mechanism; additive nephrotoxicity is only theoretical.
What to do
Monitor serum creatinine and eGFR as routine for voclosporin, and adjust the dose per labeling if renal function worsens.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Micafungin
- Lomitapide + Micafungin Moderate
- Micafungin + Saccharomyces boulardii Moderate
- Micafungin + Sirolimus Moderate
- Avapritinib + Micafungin Minor
- Finerenone + Micafungin Minor
- Isavuconazonium + Micafungin Minor
Other interactions of Voclosporin
- Clarithromycin + Voclosporin Contraindicated
- Cyclosporin + Voclosporin Contraindicated
- Ensitrelvir + Voclosporin Contraindicated
- Itraconazole + Voclosporin Contraindicated
- Ketoconazole + Voclosporin Contraindicated
- Posaconazole + Voclosporin Contraindicated
Frequently asked questions
Can I take Micafungin with Voclosporin?
MediHelp rates the interaction as minor. Micafungin and Voclosporin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Voclosporin is nephrotoxic in a dose-related manner. Micafungin has little direct nephrotoxicity, so additive harm is theoretical.
How serious is the interaction between Micafungin and Voclosporin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and eGFR as routine for voclosporin, and adjust the dose per labeling if renal function worsens.
What other medicines interact with Micafungin?
MediHelp also lists interactions of Micafungin with, for example, Lomitapide, Saccharomyces boulardii, Sirolimus. The full list is on the Micafungin page.
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