Drug interactions
Midazolam + Teduglutide
Severity: Minor
Midazolam and Teduglutide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Teduglutide improves intestinal fluid and nutrient absorption and may increase the absorption of oral drugs. Oral midazolam could reach higher concentrations and produce stronger sedation.
What this interaction means in plain words
Midazolam and Teduglutide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Midazolam belongs to Central Nervous System; Teduglutide belongs to Endocrine.
Why it happens
Enhanced intestinal absorption of oral medications due to the intestinotrophic effect of teduglutide.
What to do
Monitor sedation when oral midazolam is used and reduce the dose if effect is excessive.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Midazolam
- Atazanavir + Midazolam Contraindicated
- Cobicistat + Midazolam Contraindicated
- Darunavir + Midazolam Contraindicated
- Elvitegravir / cobicistat / emtricitabine / tenofovir df + Midazolam Contraindicated
- Fosamprenavir + Midazolam Contraindicated
- Indinavir + Midazolam Contraindicated
Other interactions of Teduglutide
- Chlordiazepoxide + Teduglutide Moderate
- Clonazepam + Teduglutide Moderate
- Colchicine + Teduglutide Moderate
- Cyclosporin + Teduglutide Moderate
- Digoxin + Teduglutide Moderate
- Ethosuximide + Teduglutide Moderate
Frequently asked questions
Can I take Midazolam with Teduglutide?
MediHelp rates the interaction as minor. Midazolam and Teduglutide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Teduglutide improves intestinal fluid and nutrient absorption and may increase the absorption of oral drugs. Oral midazolam could reach higher concentrations and produce stronger sedation.
How serious is the interaction between Midazolam and Teduglutide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor sedation when oral midazolam is used and reduce the dose if effect is excessive.
What other medicines interact with Midazolam?
MediHelp also lists interactions of Midazolam with, for example, Atazanavir, Cobicistat, Darunavir. The full list is on the Midazolam page.
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