Drug interactions
Miglitol + Ziprasidone
Severity: Minor
Miglitol and Ziprasidone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Antipsychotic therapy can worsen glucose control and may reduce the benefit of antidiabetic drugs such as miglitol. Ziprasidone has relatively little metabolic effect, so the change is usually small.
What this interaction means in plain words
Miglitol and Ziprasidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Miglitol belongs to Endocrine; Ziprasidone belongs to Central Nervous System.
Why it happens
Pharmacodynamic antagonism of glucose-lowering effect by antipsychotic-related glucose dysregulation.
What to do
Check blood glucose and HbA1c regularly and adjust diabetes therapy if control worsens.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ziprasidone
- Amiodarone + Ziprasidone Contraindicated
- Amitriptyline + Ziprasidone Contraindicated
- Arsenic trioxide + Ziprasidone Contraindicated
- Bedaquiline + Ziprasidone Contraindicated
- Chloroquine + Ziprasidone Contraindicated
- Citalopram + Ziprasidone Contraindicated
Other interactions of Miglitol
- Miglitol + Pramlintide Major
- Aripiprazole + Miglitol Moderate
- Asenapine + Miglitol Moderate
- Chlorthalidone + Miglitol Moderate
- Clozapine + Miglitol Moderate
- Cortisone + Miglitol Moderate
Frequently asked questions
Can I take Miglitol with Ziprasidone?
MediHelp rates the interaction as minor. Miglitol and Ziprasidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Antipsychotic therapy can worsen glucose control and may reduce the benefit of antidiabetic drugs such as miglitol. Ziprasidone has relatively little metabolic effect, so the change is usually small.
How serious is the interaction between Miglitol and Ziprasidone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check blood glucose and HbA1c regularly and adjust diabetes therapy if control worsens.
What other medicines interact with Ziprasidone?
MediHelp also lists interactions of Ziprasidone with, for example, Amiodarone, Amitriptyline, Arsenic trioxide. The full list is on the Ziprasidone page.
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