Drug interactions
Nabilone + Phentermine
Severity: Minor
Nabilone and Phentermine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Phentermine is a sympathomimetic stimulant that can raise heart rate and blood pressure, and nabilone commonly causes tachycardia. The combination may increase cardiovascular effects and anxiety, and phentermine does not reliably counteract nabilone sedation.
What this interaction means in plain words
Nabilone and Phentermine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Nabilone belongs to Gastrointestinal Tract; Phentermine belongs to Central Nervous System.
Why it happens
Additive tachycardic effects from sympathomimetic activity and cannabinoid receptor agonism; no established pharmacokinetic mechanism.
What to do
Monitor heart rate, blood pressure and anxiety symptoms, particularly at initiation.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Nabilone
Other interactions of Phentermine
- Isocarboxazid + Phentermine Contraindicated
- Linezolid + Phentermine Contraindicated
- Phenelzine + Phentermine Contraindicated
- Phentermine + Procarbazine Contraindicated
- Phentermine + Rasagiline Contraindicated
- Phentermine + Selegiline Contraindicated
Frequently asked questions
Can I take Nabilone with Phentermine?
MediHelp rates the interaction as minor. Nabilone and Phentermine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Phentermine is a sympathomimetic stimulant that can raise heart rate and blood pressure, and nabilone commonly causes tachycardia. The combination may increase cardiovascular effects and anxiety, and phentermine does not reliably counteract nabilone sedation.
How serious is the interaction between Nabilone and Phentermine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate, blood pressure and anxiety symptoms, particularly at initiation.
What other medicines interact with Nabilone?
MediHelp also lists interactions of Nabilone with, for example, Alfentanil, Amobarbital, Belladonna and opium. The full list is on the Nabilone page.
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