Drug interactions
Nicardipine + Paromomycin
Severity: Minor
Nicardipine and Paromomycin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral paromomycin is minimally absorbed, so an effect of P-glycoprotein inhibition on its systemic exposure is unlikely to be clinically important. No meaningful interaction is established.
What this interaction means in plain words
Nicardipine and Paromomycin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Nicardipine belongs to Cardiovascular; Paromomycin belongs to Anti Bacterial.
Why it happens
Theoretical P-glycoprotein inhibition by nicardipine; paromomycin has negligible systemic absorption orally.
What to do
No action is required for oral paromomycin. Monitor renal function in patients with renal impairment or damaged gut mucosa as usual.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Nicardipine
Other interactions of Paromomycin
- Cidofovir + Paromomycin Major
- Adefovir + Paromomycin Moderate
- Amikacin + Paromomycin Moderate
- Amphotericin b + Paromomycin Moderate
- Atracurium + Paromomycin Moderate
- Bacitracin-neomycin-polymyxin + Paromomycin Moderate
Frequently asked questions
Can I take Nicardipine with Paromomycin?
MediHelp rates the interaction as minor. Nicardipine and Paromomycin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oral paromomycin is minimally absorbed, so an effect of P-glycoprotein inhibition on its systemic exposure is unlikely to be clinically important. No meaningful interaction is established.
How serious is the interaction between Nicardipine and Paromomycin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action is required for oral paromomycin. Monitor renal function in patients with renal impairment or damaged gut mucosa as usual.
What other medicines interact with Nicardipine?
MediHelp also lists interactions of Nicardipine with, for example, Amifostine, Amlodipine-olmesartan-hydrochlorothiazide, Betrixaban. The full list is on the Nicardipine page.
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