Drug interactions
Nicardipine + Risperidone
Severity: Minor
Nicardipine and Risperidone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Nicardipine may slightly raise risperidone exposure through P-glycoprotein inhibition. Additive hypotension is also possible. Clinically significant effects are not well documented.
What this interaction means in plain words
Nicardipine and Risperidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Nicardipine belongs to Cardiovascular; Risperidone belongs to Central Nervous System.
Why it happens
Possible P-glycoprotein inhibition by nicardipine, plus additive hypotensive effects.
What to do
No routine dose change. Monitor blood pressure and for increased sedation or extrapyramidal symptoms.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Nicardipine
Other interactions of Risperidone
- Ibutilide + Risperidone Contraindicated
- Risperidone + Vandetanib Contraindicated
- Adagrasib + Risperidone Major
- Amiodarone + Risperidone Major
- Amisulpride + Risperidone Major
- Amoxapine + Risperidone Major
Frequently asked questions
Can I take Nicardipine with Risperidone?
MediHelp rates the interaction as minor. Nicardipine and Risperidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Nicardipine may slightly raise risperidone exposure through P-glycoprotein inhibition. Additive hypotension is also possible. Clinically significant effects are not well documented.
How serious is the interaction between Nicardipine and Risperidone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine dose change. Monitor blood pressure and for increased sedation or extrapyramidal symptoms.
What other medicines interact with Nicardipine?
MediHelp also lists interactions of Nicardipine with, for example, Amifostine, Amlodipine-olmesartan-hydrochlorothiazide, Betrixaban. The full list is on the Nicardipine page.
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