Drug interactions
Nitrofurantoin + Selinexor
Severity: Minor
Nitrofurantoin and Selinexor: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Selinexor commonly causes dizziness, confusion and neurological effects, and nitrofurantoin can rarely cause neuropathy and CNS effects. A clinically meaningful interaction is largely theoretical.
What this interaction means in plain words
Nitrofurantoin and Selinexor have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Nitrofurantoin belongs to Anti Bacterial; Selinexor belongs to Oncology.
Why it happens
Possible additive neurological adverse effects; no established mechanism.
What to do
Counsel patients about dizziness and confusion and monitor for neuropathy symptoms. Review the antibiotic if neurological effects emerge.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Nitrofurantoin
Other interactions of Selinexor
- Aldesleukin + Selinexor Moderate
- Alprazolam + Selinexor Moderate
- Amitriptyline + Selinexor Moderate
- Amobarbital + Selinexor Moderate
- Aripiprazole + Selinexor Moderate
- Asenapine + Selinexor Moderate
Frequently asked questions
Can I take Nitrofurantoin with Selinexor?
MediHelp rates the interaction as minor. Nitrofurantoin and Selinexor have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Selinexor commonly causes dizziness, confusion and neurological effects, and nitrofurantoin can rarely cause neuropathy and CNS effects. A clinically meaningful interaction is largely theoretical.
How serious is the interaction between Nitrofurantoin and Selinexor?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients about dizziness and confusion and monitor for neuropathy symptoms. Review the antibiotic if neurological effects emerge.
What other medicines interact with Nitrofurantoin?
MediHelp also lists interactions of Nitrofurantoin with, for example, Pexidartinib, Pretomanid, Aluminum hydroxide. The full list is on the Nitrofurantoin page.
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