Drug interactions
Omadacycline + Succinylcholine
Severity: Minor
Omadacycline and Succinylcholine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tetracycline class antibiotics have been described to weakly potentiate neuromuscular blockade. A clinically meaningful effect with omadacycline and succinylcholine is theoretical and not well documented.
What this interaction means in plain words
Omadacycline and Succinylcholine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Omadacycline belongs to Anti Bacterial; Succinylcholine belongs to Musculoskeletal.
Why it happens
Possible weak neuromuscular blocking activity of tetracyclines, extrapolated from class data; not established for omadacycline.
What to do
No routine change is needed. Monitor neuromuscular recovery as usual after succinylcholine.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Succinylcholine
Other interactions of Omadacycline
- Acitretin + Omadacycline Contraindicated
- Isotretinoin + Omadacycline Major
- Omadacycline + Tretinoin Major
- Aluminum hydroxide + Omadacycline Moderate
- Amoxicillin-clavulanic acid + Omadacycline Moderate
- Amoxicillin + Omadacycline Moderate
Frequently asked questions
Can I take Omadacycline with Succinylcholine?
MediHelp rates the interaction as minor. Omadacycline and Succinylcholine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Tetracycline class antibiotics have been described to weakly potentiate neuromuscular blockade. A clinically meaningful effect with omadacycline and succinylcholine is theoretical and not well documented.
How serious is the interaction between Omadacycline and Succinylcholine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed. Monitor neuromuscular recovery as usual after succinylcholine.
What other medicines interact with Succinylcholine?
MediHelp also lists interactions of Succinylcholine with, for example, Amikacin, Bacitracin-neomycin-polymyxin, Capreomycin. The full list is on the Succinylcholine page.
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