Drug interactions
Oxymorphone + Propylhexedrine
Severity: Minor
Oxymorphone and Propylhexedrine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Propylhexedrine is a topical nasal decongestant with a mild sympathomimetic effect. Systemic exposure is small, and no clinically significant interaction with oxymorphone is established.
What this interaction means in plain words
Oxymorphone and Propylhexedrine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Oxymorphone belongs to Musculoskeletal; Propylhexedrine belongs to Respiratory.
Why it happens
No established mechanism; any effect would be a minor opposing pharmacodynamic one.
What to do
No specific action is needed; monitor opioid effects routinely.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Oxymorphone
- Alvimopan + Oxymorphone Contraindicated
- Ethanol + Oxymorphone Contraindicated
- Isocarboxazid + Oxymorphone Contraindicated
- Olanzapine / samidorphan + Oxymorphone Contraindicated
- Oxymorphone + Phenelzine Contraindicated
- Oxymorphone + Selegiline transdermal Contraindicated
Other interactions of Propylhexedrine
- Isocarboxazid + Propylhexedrine Contraindicated
- Phenelzine + Propylhexedrine Contraindicated
- Linezolid + Propylhexedrine Major
- Propylhexedrine + Selegiline Major
- Propylhexedrine + Tranylcypromine Major
- Adrenaline-articaine + Propylhexedrine Moderate
Frequently asked questions
Can I take Oxymorphone with Propylhexedrine?
MediHelp rates the interaction as minor. Oxymorphone and Propylhexedrine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Propylhexedrine is a topical nasal decongestant with a mild sympathomimetic effect. Systemic exposure is small, and no clinically significant interaction with oxymorphone is established.
How serious is the interaction between Oxymorphone and Propylhexedrine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is needed; monitor opioid effects routinely.
What other medicines interact with Oxymorphone?
MediHelp also lists interactions of Oxymorphone with, for example, Alvimopan, Ethanol, Isocarboxazid. The full list is on the Oxymorphone page.
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