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Drug interactions

Papaverine + Temazepam

Severity: Minor

Papaverine and Temazepam: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Temazepam is a benzodiazepine hypnotic that causes sedation and impaired psychomotor performance. Papaverine may add slightly to drowsiness, though the effect is expected to be small.

What this interaction means in plain words

Papaverine and Temazepam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Papaverine belongs to Cardiovascular; Temazepam belongs to Central Nervous System.

Evidence level: Low

Why it happens

Possible additive CNS depression; papaverine's contribution is weak.

What to do

Counsel patients about drowsiness and avoiding driving or hazardous tasks. Use the lowest effective temazepam dose, especially in older adults.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Papaverine with Temazepam?

MediHelp rates the interaction as minor. Papaverine and Temazepam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Temazepam is a benzodiazepine hypnotic that causes sedation and impaired psychomotor performance. Papaverine may add slightly to drowsiness, though the effect is expected to be small.

How serious is the interaction between Papaverine and Temazepam?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients about drowsiness and avoiding driving or hazardous tasks. Use the lowest effective temazepam dose, especially in older adults.

What other medicines interact with Papaverine?

MediHelp also lists interactions of Papaverine with, for example, Givinostat, Bretylium, Calcium / magnesium / potassium / sodium oxybates. The full list is on the Papaverine page.

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

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