Drug interactions
Paromomycin + Quinidine
Severity: Minor
Paromomycin and Quinidine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral paromomycin is minimally absorbed, so a P-glycoprotein interaction with quinidine is unlikely to be clinically meaningful. No established effect on either drug is documented.
What this interaction means in plain words
Paromomycin and Quinidine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Paromomycin belongs to Anti Bacterial; Quinidine belongs to Anti Parasitic.
Why it happens
Theoretical P-glycoprotein inhibition by quinidine, with negligible systemic paromomycin exposure.
What to do
No specific action is needed beyond routine monitoring of renal function and quinidine therapy.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Quinidine
- Adagrasib + Quinidine Contraindicated
- Arsenic trioxide + Quinidine Contraindicated
- Artemether / lumefantrine + Quinidine Contraindicated
- Chloroquine + Quinidine Contraindicated
- Dofetilide + Quinidine Contraindicated
- Dronedarone + Quinidine Contraindicated
Other interactions of Paromomycin
- Cidofovir + Paromomycin Major
- Adefovir + Paromomycin Moderate
- Amikacin + Paromomycin Moderate
- Amphotericin b + Paromomycin Moderate
- Atracurium + Paromomycin Moderate
- Bacitracin-neomycin-polymyxin + Paromomycin Moderate
Frequently asked questions
Can I take Paromomycin with Quinidine?
MediHelp rates the interaction as minor. Paromomycin and Quinidine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oral paromomycin is minimally absorbed, so a P-glycoprotein interaction with quinidine is unlikely to be clinically meaningful. No established effect on either drug is documented.
How serious is the interaction between Paromomycin and Quinidine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is needed beyond routine monitoring of renal function and quinidine therapy.
What other medicines interact with Quinidine?
MediHelp also lists interactions of Quinidine with, for example, Adagrasib, Arsenic trioxide, Artemether / lumefantrine. The full list is on the Quinidine page.
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