Drug interactions
Piroxicam + Potassium iodide
Severity: Minor
Piroxicam and Potassium iodide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Potassium iodide supplies potassium, and NSAIDs reduce renal potassium excretion, so serum potassium may rise, particularly in renal impairment or with other potassium-raising drugs.
What this interaction means in plain words
Piroxicam and Potassium iodide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Piroxicam belongs to Musculoskeletal; Potassium iodide belongs to Endocrine.
Why it happens
NSAID-induced suppression of renin-aldosterone axis and reduced renal potassium excretion adds to the potassium load.
What to do
Monitor serum potassium in patients with renal impairment or on other hyperkalemia-promoting drugs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Piroxicam
- Ketorolac intranasal + Piroxicam Contraindicated
- Ketorolac + Piroxicam Contraindicated
- Aceclofenac + Piroxicam Major
- Acemetacin + Piroxicam Major
- Acetylsalicylic acid + Piroxicam Major
- Alteplase + Piroxicam Major
Other interactions of Potassium iodide
- Amiloride + Potassium iodide Moderate
- Amlodipine-benazepril + Potassium iodide Moderate
- Amlodipine-hydrochlorothiazide-valsartan + Potassium iodide Moderate
- Amlodipine-olmesartan-hydrochlorothiazide + Potassium iodide Moderate
- Amlodipine-olmesartan + Potassium iodide Moderate
- Amlodipine-perindopril + Potassium iodide Moderate
Frequently asked questions
Can I take Piroxicam with Potassium iodide?
MediHelp rates the interaction as minor. Piroxicam and Potassium iodide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Potassium iodide supplies potassium, and NSAIDs reduce renal potassium excretion, so serum potassium may rise, particularly in renal impairment or with other potassium-raising drugs.
How serious is the interaction between Piroxicam and Potassium iodide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium in patients with renal impairment or on other hyperkalemia-promoting drugs.
What other medicines interact with Piroxicam?
MediHelp also lists interactions of Piroxicam with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Piroxicam page.
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