Drug interactions
Pneumococcal vaccine 13-valent + Temsirolimus
Severity: Minor
Pneumococcal vaccine 13-valent and Temsirolimus: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Temsirolimus is immunosuppressive and may blunt antibody response to the vaccine. The vaccine is inactivated, so there is no infection risk from the vaccine itself, and it is not contraindicated.
What this interaction means in plain words
Pneumococcal vaccine 13-valent and Temsirolimus have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Pneumococcal vaccine 13-valent belongs to Miscellaneous; Temsirolimus belongs to Oncology.
Why it happens
Immunosuppression by mTOR inhibition may reduce vaccine immunogenicity.
What to do
Vaccinate ideally before starting temsirolimus when feasible; otherwise give the vaccine per schedule and do not withhold it.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Pneumococcal vaccine 13-valent and Temsirolimus, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Temsirolimus
- Bcg vaccine live + Temsirolimus Contraindicated
- Influenza virus vaccine quadrivalent intranasal + Temsirolimus Contraindicated
- Measles mumps and rubella vaccine live + Temsirolimus Contraindicated
- Measles mumps rubella and varicella vaccine live + Temsirolimus Contraindicated
- Measles vaccine + Temsirolimus Contraindicated
- Rotavirus oral vaccine live + Temsirolimus Contraindicated
Other interactions of Pneumococcal vaccine 13-valent
- Adalimumab + Pneumococcal vaccine 13-valent Moderate
- Alefacept + Pneumococcal vaccine 13-valent Moderate
- Anakinra + Pneumococcal vaccine 13-valent Moderate
- Anti-thymocyte + Pneumococcal vaccine 13-valent Moderate
- Antithymocyte globulin equine + Pneumococcal vaccine 13-valent Moderate
- Antithymocyte globulin rabbit + Pneumococcal vaccine 13-valent Moderate
Frequently asked questions
Can I take Pneumococcal vaccine 13-valent with Temsirolimus?
MediHelp rates the interaction as minor. Pneumococcal vaccine 13-valent and Temsirolimus have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Temsirolimus is immunosuppressive and may blunt antibody response to the vaccine. The vaccine is inactivated, so there is no infection risk from the vaccine itself, and it is not contraindicated.
How serious is the interaction between Pneumococcal vaccine 13-valent and Temsirolimus?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate ideally before starting temsirolimus when feasible; otherwise give the vaccine per schedule and do not withhold it.
What other medicines interact with Temsirolimus?
MediHelp also lists interactions of Temsirolimus with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine live. The full list is on the Temsirolimus page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
