Drug interactions
Quercetin + Silodosin
Severity: Minor
Quercetin and Silodosin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Quercetin may modulate P-glycoprotein activity in vitro, but the direction and magnitude in humans are uncertain. A meaningful change in silodosin exposure has not been well demonstrated.
What this interaction means in plain words
Quercetin and Silodosin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible modulation of P-glycoprotein by quercetin; the effect on silodosin is not established.
What to do
No dose change is needed. Review symptom control and tolerability if the patient takes high-dose quercetin supplements.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Silodosin
- Atazanavir + Silodosin Contraindicated
- Conivaptan + Silodosin Contraindicated
- Darunavir + Silodosin Contraindicated
- Fosamprenavir + Silodosin Contraindicated
- Indinavir + Silodosin Contraindicated
- Itraconazole + Silodosin Contraindicated
Frequently asked questions
Can I take Quercetin with Silodosin?
MediHelp rates the interaction as minor. Quercetin and Silodosin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Quercetin may modulate P-glycoprotein activity in vitro, but the direction and magnitude in humans are uncertain. A meaningful change in silodosin exposure has not been well demonstrated.
How serious is the interaction between Quercetin and Silodosin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is needed. Review symptom control and tolerability if the patient takes high-dose quercetin supplements.
What other medicines interact with Silodosin?
MediHelp also lists interactions of Silodosin with, for example, Atazanavir, Conivaptan, Darunavir. The full list is on the Silodosin page.
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