Drug interactions
Quetiapine + Triclabendazole
Severity: Moderate
Quetiapine and Triclabendazole: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Triclabendazole has been associated with QT prolongation, and quetiapine may add to this effect. The risk of arrhythmia is mainly relevant in patients with other cardiac or electrolyte risk factors.
What this interaction means in plain words
Quetiapine and Triclabendazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Quetiapine belongs to Central Nervous System; Triclabendazole belongs to Anti Parasitic.
Why it happens
Additive QT interval prolongation.
What to do
Obtain a baseline ECG and correct electrolyte abnormalities in patients with QT risk factors. Avoid the combination in congenital long QT syndrome.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Quetiapine
- Adagrasib + Quetiapine Major
- Amiodarone + Quetiapine Major
- Amisulpride + Quetiapine Major
- Amoxapine + Quetiapine Major
- Anagrelide + Quetiapine Major
- Apalutamide + Quetiapine Major
Other interactions of Triclabendazole
Frequently asked questions
Can I take Quetiapine with Triclabendazole?
MediHelp rates the interaction as moderate. Quetiapine and Triclabendazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Triclabendazole has been associated with QT prolongation, and quetiapine may add to this effect. The risk of arrhythmia is mainly relevant in patients with other cardiac or electrolyte risk factors.
How serious is the interaction between Quetiapine and Triclabendazole?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain a baseline ECG and correct electrolyte abnormalities in patients with QT risk factors. Avoid the combination in congenital long QT syndrome.
What other medicines interact with Quetiapine?
MediHelp also lists interactions of Quetiapine with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Quetiapine page.
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