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Drug interactions

Radium-223 dichloride + Vitamin d

Severity: Minor

Radium-223 dichloride and Vitamin d: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Radium-223 is a calcium mimetic that accumulates in bone. Calcium and vitamin D supplements might theoretically compete with radium uptake, but no clinically meaningful effect has been established.

What this interaction means in plain words

Radium-223 dichloride and Vitamin d have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Radium-223 dichloride belongs to Miscellaneous; Vitamin d belongs to Gastrointestinal Tract.

Evidence level: Low

Why it happens

Theoretical competition for bone uptake between radium and calcium; not well established clinically.

What to do

No routine change is needed; supplements may be continued when clinically indicated, and the prescriber may consider a short pause only if supplementation is not essential.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Radium-223 dichloride with Vitamin d?

MediHelp rates the interaction as minor. Radium-223 dichloride and Vitamin d have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Radium-223 is a calcium mimetic that accumulates in bone. Calcium and vitamin D supplements might theoretically compete with radium uptake, but no clinically meaningful effect has been established.

How serious is the interaction between Radium-223 dichloride and Vitamin d?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed; supplements may be continued when clinically indicated, and the prescriber may consider a short pause only if supplementation is not essential.

What other medicines interact with Radium-223 dichloride?

MediHelp also lists interactions of Radium-223 dichloride with, for example, Abiraterone, Prednisolone, Prednisone. The full list is on the Radium-223 dichloride page.

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