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Drug interactions

Ropinirole + Teriflunomide

Severity: Minor

Ropinirole and Teriflunomide: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Teriflunomide is a weak CYP1A2 inducer and may modestly lower exposure to CYP1A2 substrates such as ropinirole. Loss of symptom control is possible but usually small.

What this interaction means in plain words

Ropinirole and Teriflunomide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Ropinirole belongs to Central Nervous System; Teriflunomide belongs to Central Nervous System.

Evidence level: Moderate

Why it happens

Teriflunomide weakly induces CYP1A2, increasing ropinirole metabolism.

What to do

Monitor symptom control and adjust ropinirole dose if the response declines.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Ropinirole with Teriflunomide?

MediHelp rates the interaction as minor. Ropinirole and Teriflunomide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Teriflunomide is a weak CYP1A2 inducer and may modestly lower exposure to CYP1A2 substrates such as ropinirole. Loss of symptom control is possible but usually small.

How serious is the interaction between Ropinirole and Teriflunomide?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor symptom control and adjust ropinirole dose if the response declines.

What other medicines interact with Ropinirole?

MediHelp also lists interactions of Ropinirole with, for example, Amisulpride, Chlorpromazine, Droperidol. The full list is on the Ropinirole page.

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